Zeitschrift für klinische Onkologie und Krebsforschung

Abstrakt

A 59-year-old man with primary thyroid leiomyosarcoma: A case report.

Aram Behdadnia, Marjan Jeddi, Amirreza Dehghanian, Shahram Paydar

Introduction: Leiomyosarcoma is a rare tumor of the thyroid gland. The preoperative diagnosis with fine needle aspiration is difficult. It can be either primary or metastatic. Case presentation: A 59-year-old man presented with a rapidly progressive rubbery mass-like lesion in the anterior part of the neck in about 6 months accompanied by weight loss. He was euthyroid and had a family history of papillary thyroid cancer in his uncle. Total thyroidectomy was performed, and pathologic findings demonstrated primary thyroid Leiomyosarcoma (LMS). After tumor surveillance and oncology consultation, he was planned for chemotherapy. Conclusion: Leiomyosarcoma should be suspected in any rapidly progressive mass in the anterior part of the neck. Anaplastic, medullary thyroid carcinoma and metastatic source are among the differential diagnoses. Thyroidectomy may be required for definite diagnosis. There is no consensus regarding the optimal treatment. Despite advanced diagnostic and treatment approach, prognosis is poor.