Abstrakt

Adult-Onset Still`s Disease Presenting with Recurrent Fever and Sore Throat.

Alaaeldin Y Alhessi

Adult-onset Still?s Disease (AOSD) is a rare systemic auto inflammatory disorder characterized by a triad of spiking fever, rash, and arthralgia that may be associated with multiple systemic manifestations.Diagnosis is clinical, which can be challenging. While definitive diagnostic test is lacking, ferritin and glycosylated ferritin are useful adjuncts to aid in the diagnosis of AOSD. It is important to include AOSD in the differential diagnosis of prolonged fever and sore throat especially if accompanied by other systemic manifestations.Mainstay treatment of AOSD is often with glucocorticoids. Other agents that can also be used include methotrexate, and biologic therapy, such as tumor necrosis factor-? (TNF-?) blockers and interleukin-1 (IL-1) inhibitors. We hereby report a case of a thirty-six years old man who presented with a prolonged course of fever, and recurrent pharyngitis diagnosed as Adult-onset Still?s Disease (AOSD).