Abstrakt

Effect of lupeol on the expression of neuro inflammatory signalling molecules in brain tissues of high fat diet and sucrose fed type 2 diabetic rats

Esha Gayathri, V Vishnu Priya*, J Selvaraj, Gayathri R, Kavitha S

Lupeol has the anti- inflammatory, antimicrobial, anti-protozoal, anti-proliferative, anti- invasion, anti-angiogenic and cholesterol lowering properties. Lupeol has also been studied for its therapeutic efficacy in a variety of in vitro and in vivo models, including wound healing, diabetes, cardiovascular disease, kidney disease and arthritis. It has also been shown to be pharmacologically effective in the treatment of a number of diseases in preclinical settings. However, the mechanisms underlying the effect of lupeol on neuroinflammatory signaling molecules has not yet been identified.