Abstrakt

Effect of p53 gene in the cancer

Leonard Lee

p53 gene was also known to be TP53 gene. In some cases it was called as tumour protein. It is a gene that helps in coding for a protein that is responsible in control and regulation of the cell division and cell cycle. As we all know that tumour is result of uncontrolled cell division, as this p53 gene helps in regulation of cell division it is also referred to as tumour suppressor gene. p53 gene is also known as guardian of the genome as it plays a key role in protecting the cell from mutations. The protein has a molecular weight of 53 Kilo Daltons so it is called as p53 gene. The p53 gene is located on 17th chromosome of human DNA