Abstrakt

Intelligent design, synthesis and validation of drug delivery systems targeted against breast cancer stem cells

Petra Gener

Tumor recurrence, metastatic spread and progressive gain of chemo-resistance of advanced cancers are sustained by the presence of Cancer Stem Cells (CSCs) within the tumor. Targeted therapies with the aim to eradicate these cells are thus highly regarded. However, often the use of new anti-cancer therapies is hampered by pharmacokinetic demands. Drug delivery