Abstrakt

Isolation and antibiotic resistance pattern of vancomycin-resistant Enterococcus fascium strains in clinical samples in Tabriz hospitals.

Jafari-Sales A, Tarbiat-Nazloo D, Shadi-Dizaji A

Background: In recent decades, Enterococci have been identified as an important pathogen. Resistance of these bacteria to antibiotics causes major problems in the therapeutic process. Therefore, the aim of this study was to determine the antibiotic resistance pattern of Enterococcus fascium strain in clinical samples. Methods: In this research, 219 samples of Enterococci from clinical specimens including: Blood and urine were studied in Tabriz hospitals. All strains were identified by standard and bacteriological tests, and then antibiotic resistance patterns of bacteria isolated by Kirby-Bauer disc diffusion method were performed. Also, the minimum inhibitory concentration (MIC) was determined by E-Test method. Results: Of 219 strains of Enterococcus, 86 (39.26%) strains belong to the species of E. fascium. The highest resistance to antibiotics was tetracycline (83.7%) and erythromycin (65.1%), and lowest compared to linezolid (0%) and teicoplanin (18.6%). Based on the E-Test, 29 (33.7%) sample was resistant to vancomycin. Conclusion: Considering the increasing number of infectious diseases caused by resistant strains of Enterococcus genus and its dissemination in the hospital environment, it is very necessary to use infection control measures to eliminate the potential sources of infection and prevent it from developing.