Abstrakt

New insights on the pain of bone cancer.

Xiaolu Li

Poor quality of life is typically experienced by patients with primary bone sarcomas and malignant tumours that have metastasized to the bone (QOL). Skeletal fractures resulting from osteosis, hypercalcaemia, neurologic compression, depression, sleeplessness, and the discomfort of bone cancer can all be hindrances to enjoying life. One of the most typical symptoms that cancer patients report is discomfort from their bones. The prevalence of cancer-related bone discomfort is primarily attributed to metastatic breast and prostate carcinomas. In over 70% of individuals with advanced breast or prostate cancer, skeletal problems as a result of metastatic illness emerge. Furthermore, more than 90% of individuals with breast or prostate cancer who pass away have skeletal metastases. The unpleasant impression of sensory stimuli which are not frequently considered as harmful is known as tactile allodynia. The emergence of this kind of pain pierces the bone cancer pain pathway. This severe case of movement-evoked pain can be brought on by infrequent limb movement, coughing, or turning over in bed and is less responsive to standard treatments.