Abstrakt

Frequency of adverse drug effects appears superficially to be higher in intensive care units and emergency

Amir Hussain

The occurrence of severe or fatal adverse drug reactions is extremely low (usually 1 in 1000) and may go undetected during clinical trials, which are not normally powered to detect low-incidence ADRs. As a result, many ADRs may not be recognised until after a medicine has been introduced to the general public and is widely used. Generally speaking an adverse drug event (ADE) occurs when a medication causes harm. Older folks (65 and above) attend emergency departments nearly 450,000 times every year, more than twice as frequently as younger people. Although allergic reactions are the most common form of antibiotic-associated adverse medication event, avoiding unnecessary antibiotic use is the greatest method to limit the risk of antibiotic-related adverse drug events.